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Life's Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening
Wenqiang Li1, Youli Wen1, Yuting Fan2
1Department of Respiratory and Critical Care Medicine, Zigong First People's Hospital, Zigong, Sichuan Province, 643000, People's Republic of China.
Purpose:
This study aims to investigate the association between the Life's Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.
Patients And Methods:
We screened the NHANES database for data from 2007-2018. Logistic regression analysis and subgroup analysis were used to explore the association between LC9 score and COPD in middle-aged and older adults. Additionally, restricted cubic spline (RCS) was plotted to visually depict the dose-response relationship between the two.
Results:
A total of 12,030 participants were included, of whom 815 had COPD. After multivariate adjustment, the LC9 score was found to be inversely associated with COPD diagnosis. The RCS visually demonstrated a linear decreasing relationship between the two. Furthermore, subgroup analysis revealed no significant interaction across different subgroups, except for education level.
Conclusion:
The LC9 score is linearly and inversely associated with COPD diagnosis. Higher LC9 scores are associated with a lower COPD diagnosis in individuals aged 40 and above.
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