Related Experiment Video
Updated: Sep 16, 2025
Terahertz Imaging and Characterization Protocol for Freshly Excised Breast Cancer Tumors
Published on: April 5, 2020
Terahertz Photonic Crystal Fiber Sensor for Cancer Cell Detection: Performance Analysis and Discrimination
Kayab Khandakar1, Md Omar Faruk1, A H M Iftekharul Ferdous1
1Electrical and Electronic Engineering Department, Pabna University of Science and Technology, Pabna, Bangladesh.
Background:
Cancer cells exhibit significant heterogeneity, making their detection a challenging task.
Methods:
In this study, a unique Photonic Crystal Fiber (PCF) sensor with a circular core design and curved trapezoidal cladding is presented. It is especially designed to detect cancer cells efficiently.
Results:
The proposed sensor demonstrates exceptional performance, achieving a maximum relative sensitivity (RS) of 99.71% for breast cancer type II cells, along with similarly high sensitivities for cervical, adrenal gland, skin, blood, and breast cancer type I cells. Key performance parameters highlight its accuracy in detecting cancer cells via minute changes in refractive index (RI), including ultra-low confinement loss (CL) of up to 6.69 × 10-13 dB/cm and effective material loss (EML) as low as 0.00161 cm-1.
Conclusions:
The sensor's high accuracy, rapid response time, and ability to selectively target tumor cells make it a breakthrough in early cancer detection. Moreover, its compact size and potential for easy fabrication enhance its applicability in emergency settings. This cutting-edge approach represents a major advancement in medical technology, paving the way for more efficient and targeted cancer diagnostics.
