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Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Mechanisms of Retrovirus-induced Cancers01:51

Mechanisms of Retrovirus-induced Cancers

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Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
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Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

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Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Preventive Healthcare Services01:30

Preventive Healthcare Services

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Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
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3D Cell-Printed Hypoxic Cancer-on-a-Chip for Recapitulating Pathologic Progression of Solid Cancer
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Preventable Cancers Caused by Infection in Korea From 2015 to 2030.

Sungji Moon1,2,3,4, Jeoungbin Choi1, Soseul Sung1,2,5

  • 1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.

Journal of Korean Medical Science
|July 8, 2025
PubMed
Summary

Infection-related cancers in South Korea are projected to decrease, with significant contributions from Helicobacter pylori, hepatitis B virus (HBV), and human papillomavirus (HPV). Public health interventions are crucial for further reducing cancer burden.

Keywords:
20152020CancerInfectious AgentsPopulation Attributable FractionSouth Korea

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Area of Science:

  • Oncology
  • Infectious Diseases
  • Public Health Policy

Background:

  • Cancer prevention policies require understanding the burden of infection-related cancers.
  • Estimating the population-attributable fraction (PAF) of cancers linked to infectious agents is essential for evidence-based policy.
  • This study assesses infection-related cancer burden in South Korea from 2015 to 2030.

Purpose of the Study:

  • To systematically estimate the burden of infection-related cancers in South Korea.
  • To calculate the population-attributable fraction (PAF) for cancers caused by infectious agents.
  • To project trends in infection-related cancer incidence and mortality up to 2030.

Main Methods:

  • Meta-analysis of Korean cohort studies and systematic review of South Korean studies to determine relative risks.
  • Calculation of attributable cancer incidence and mortality using nationwide cancer statistics (2015-2020).
  • Projection of cancer burden for 2025 and 2030, assuming a 15-year latency period.

Main Results:

  • Infection-related cancers accounted for 13.18% of cases and 14.74% of deaths in 2015, decreasing to 10.70% and 12.15% by 2020.
  • Helicobacter pylori, hepatitis B virus (HBV), and human papillomavirus (HPV) were the leading infectious agents.
  • PAF for incidence and mortality are predicted to decline further by 2030.

Conclusions:

  • The proportion of cancer cases and deaths attributable to infectious agents is expected to decrease between 2015 and 2030.
  • Targeted interventions against H. pylori, HBV, and HPV are recommended to reduce the overall cancer burden.
  • Continued monitoring and public health initiatives are vital for effective cancer prevention.