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Long-Term Survival after Choroidal Metastasis Following Colorectal Cancer Surgery: A Case Report
Keiichiro Ryujin1, Tetsuro Kawazoe1, Shota Sato1
1Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan.
Surgical Case Reports
|July 8, 2025
Summary
Choroidal metastasis from colorectal cancer is rare but requires prompt diagnosis. Combining systemic therapy with local treatments can improve quality of life and prolong survival for patients with ocular tumors.
Area of Science:
- Oncology
- Ophthalmology
Background:
- Choroidal metastasis from colorectal cancer is a rare but increasingly recognized clinical entity.
- Improved survival rates in colorectal cancer necessitate greater awareness of potential ocular metastases.
Observation:
- A 67-year-old man with a history of ascending colon cancer developed visual impairment due to choroidal metastasis.
- The patient had previously undergone surgery and chemotherapy for colon cancer and had a pulmonary recurrence.
Findings:
- A combination of systemic chemotherapy and local radiotherapy led to tumor shrinkage and symptom relief.
- Review of 22 cases since 2000 showed most patients had widespread metastases and an average survival of 10.4 months post-diagnosis.
- This case highlights long-term survival achieved through integrated local therapies.
Implications:
- Early detection and management of ocular metastases are crucial for colorectal cancer patients.
- A multidisciplinary approach integrating systemic and local treatments is vital for enhancing quality of life and survival outcomes.

