Antibacterial Potential of Vatica diospyroides Flower Extracts: Targeting Diverse Pathogens in Aquaculture
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View abstract on PubMed
Summary
This summary is machine-generated.Vatica diospyroides flower extracts show significant antibacterial potential against various bacterial strains. This study explored its mechanisms, revealing dose- and time-dependent effects and structural cell damage.
Area Of Science
- Pharmacology and Microbiology
- Natural Product Chemistry
Background
- Vatica diospyroides, an endemic Dipterocarpaceae species, has known medicinal properties.
- Limited research exists on the antibacterial activity of its flower extracts.
- This study addresses the gap in understanding V. diospyroides flower extract's antibacterial mechanisms.
Purpose Of The Study
- To investigate the antibacterial mechanisms of Vatica diospyroides flower extracts.
- To evaluate the efficacy of these extracts against four different bacterial strains.
- To determine the dose- and time-dependent effects of the extract on bacterial cells.
Main Methods
- Acetone extracts from V. diospyroides flowers were prepared.
- Antibacterial activity was assessed using well-disk diffusion, MIC, and MBC assays.
- Bacterial cell responses were analyzed via flow cytometry and scanning electron microscopy.
Main Results
- Inhibition zones ranged from 6.33 to 17.66 mm.
- Minimum Inhibitory Concentration (MIC) values varied, with V. parahaemolyticus being most susceptible (62.5 μg/mL).
- Flow cytometry and SEM confirmed dose- and time-dependent antibacterial effects, including structural cell damage.
Conclusions
- Vatica diospyroides flower extracts exhibit promising broad-spectrum antibacterial activity.
- The extract demonstrates dose- and time-dependent effects on bacterial viability and structure.
- Further research into V. diospyroides flower extracts could lead to novel antibacterial agents.
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