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Related Experiment Videos

Neurologic signs in senescence.

L R Jenkyn, A G Reeves, T Warren

    Archives of Neurology
    |December 1, 1985
    PubMed
    Summary
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    Neurologic test abnormalities are uncommon in healthy aging until age 70. After 70, abnormal responses and the number of signs increase significantly in older adults.

    Area of Science:

    • Gerontology
    • Neurology
    • Clinical Neuroscience

    Background:

    • Aging is associated with changes in neurologic function.
    • Establishing normative data for neurologic tests in older adults is crucial for distinguishing normal aging from pathology.
    • Previous studies have not comprehensively assessed neurologic test performance across a wide age range in healthy individuals.

    Purpose of the Study:

    • To determine the frequency of abnormal responses on nine bedside neurologic tests in healthy aging.
    • To establish normative data for these tests in individuals aged 50 to 93 years.
    • To identify age-related changes in neurologic test performance.

    Main Methods:

    • Cross-sectional study involving 2,029 healthy volunteers aged 50 to 93 years.

    Related Experiment Videos

  • Administration of nine standardized bedside neurologic tests.
  • Analysis of response frequencies and number of abnormal signs per subject.

    • Main Results:

    • Abnormal neurologic test responses remained infrequent until approximately age 70.
    • A significant increase in the rate of abnormal responses was observed after age 70.
    • The number of abnormal neurologic signs per individual also increased notably in participants over 70 years of age.

    Conclusions:

    • Neurologic test abnormalities are not a universal feature of uncomplicated aging before 70.
    • Age over 70 is associated with a higher prevalence of abnormal bedside neurologic findings.
    • These findings provide essential normative data for using bedside neurologic tests as screening tools for diffuse cerebral dysfunction in older populations.