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Neurologic signs in senescence.

L R Jenkyn, A G Reeves, T Warren

Archives of Neurology

|December 1, 1985

Summary

Neurologic test abnormalities are uncommon in healthy aging until age 70. After 70, abnormal responses and the number of signs increase significantly in older adults.

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Area of Science:

Gerontology
Neurology
Clinical Neuroscience

Background:

Aging is associated with changes in neurologic function.
Establishing normative data for neurologic tests in older adults is crucial for distinguishing normal aging from pathology.
Previous studies have not comprehensively assessed neurologic test performance across a wide age range in healthy individuals.

Purpose of the Study:

To determine the frequency of abnormal responses on nine bedside neurologic tests in healthy aging.
To establish normative data for these tests in individuals aged 50 to 93 years.
To identify age-related changes in neurologic test performance.

Main Methods:

Cross-sectional study involving 2,029 healthy volunteers aged 50 to 93 years.
Administration of nine standardized bedside neurologic tests.
Analysis of response frequencies and number of abnormal signs per subject.

Main Results:

Abnormal neurologic test responses remained infrequent until approximately age 70.
A significant increase in the rate of abnormal responses was observed after age 70.
The number of abnormal neurologic signs per individual also increased notably in participants over 70 years of age.

Conclusions:

Neurologic test abnormalities are not a universal feature of uncomplicated aging before 70.
Age over 70 is associated with a higher prevalence of abnormal bedside neurologic findings.
These findings provide essential normative data for using bedside neurologic tests as screening tools for diffuse cerebral dysfunction in older populations.