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Updated: Sep 16, 2025

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
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High-pressure activation for the solvent- and catalyst-free syntheses of heterocycles, pharmaceuticals and esters

Kelsey Plasse1, Valerie Wright1, Guoshu Xie1

  • 1Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd, Boston, MA, USA.

Beilstein Journal of Organic Chemistry
|July 8, 2025
PubMed

Keywords:
acetaminophenacetylsalicylic acidbenzimidazolescatalyst-free synthesiscyclizationestershigh hydrostatic pressurepyrazoles

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