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Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording

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3D-printed accessories for nano/microelectrodes.

Cody W Leasor¹, Kelly L Vernon¹, Yunong Wang¹

¹Department of Chemistry, Texas A&M University, College Station, TX, 77845, USA. lane.baker@tamu.edu.

Analytical Methods : Advancing Methods and Applications

|July 8, 2025

Summary

This summary is machine-generated.

Researchers developed cost-effective 3D-printed centrifuge and electrode holders for micro/nanoelectrodes. These custom tools enhance measurement science applications, offering design flexibility and overcoming commercial availability challenges.

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Area of Science:

Measurement Science
Materials Science
Engineering

Background:

Rapid prototyping and 3D printing are increasingly vital for scientific measurement tools.
Commercial electrode holders can present availability and design limitations.

Purpose of the Study:

To demonstrate the economical production and application of 3D-printed centrifuge and electrode holders.
To provide customizable solutions for micro and nanoelectrode manipulation in measurement science.

Main Methods:

Utilizing fused deposition modeling (FDM) or similar 3D printing technologies for fabricating custom holders.
Designing and printing specialized centrifuge holders for pipette filling.
Designing and printing electrode holders for electroanalytical probe characterization and scanning ion conductance microscopy.

Main Results:

Successfully produced economical 3D-printed centrifuge holders that facilitate precise pipette fluid handling.
Developed versatile 3D-printed electrode holders applicable to electroanalytical characterization.
Demonstrated the utility of 3D-printed holders in scanning ion conductance microscopy experiments.

Conclusions:

3D-printed holders offer a flexible, cost-effective alternative to commercial options for micro/nanoelectrode applications.
This approach expands the toolkit for measurement science, enabling custom configurations and overcoming supply chain issues.
The demonstrated holders are valuable for pipette handling, electroanalysis, and advanced microscopy techniques.