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Updated: Sep 16, 2025

Murine Kidney Transplant Technique
Published on: October 20, 2015
Male Breast Cancer After Kidney Transplant: Case Report and Literature Revue
Hanen Chaker1, Soumaya Yaich, Hanen Abid
1From the Nephrology Department, Hedi Chaker University Hospital; the 2Renal Pathology Research Laboratory, Faculty of Medicine of Sfax, University of Sfax, Tunisia.
Abstract:
Long-term immunosuppression can lead to malignant tumors after kidney transplant. In this case study, we report a rare case of breast cancer occurring in a man after 33 years of kidney transplant. This 55-year-old kidney transplant patient presented with a right breast mass. The biopsy showed an infiltrating carcinoma. The immunohistochemical study was positive for estrogen. The patient underwent a right mastectomy with axillary dissection. Chemotherapy based on docetaxel and radiotherapy was started. Adjuvant treatment with tamoxifen and a switch from azathioprine to sirolimus were conducted. Follow-up showed that the patient died 24 months after presentation. Through this case, we emphasize the importance of vigilance about this rare cancer, often diagnosed at a late stage, which can negatively affect prognosis. Screening for risk factors is crucial.
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