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[Is the megaesophagus test valid for White Swiss Shepherds (Berger Blanc Suisse)?]
1Laboklin GmbH & CO.KG, Bad Kissingen.
Introduction:
Gene tests play an important role for controlling monogenetic diseases because they reveal a genotype for each tested dog and thereby allow for the selection of animals with a lower genetic burden. For some complex inherited diseases and anomalies so called risk-tests are available and may support the selection of breeding animals. They analyze DNA-sequence variants which render a higher risk for carriers to develop a disease or anomaly. The usefulness of a risk-test for congenital idiopathic megaoesophagus (CIM-test) in German shepherds was analyzed in the closely related breed of White Swiss shepherds. The results showed clearly that the CIM-test in this breed is almost not informative, and a selection would probably not reduce the prevalence but only lower the genetic variability. Breeders and owners should be informed accordingly.
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