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Psychosocial Distress, Depression and Burden Among Primary Caregivers of Children With Steroid-Sensitive Nephrotic

Mritunjay Kumar1, Rashmi Kumari2, Rashmi Shukla3

  • 1Department of Pediatrics, All India Institute of Medical Sciences, Raebareli, Uttar Pradesh, 229405, India. drmkumar409@gmail.com.

Indian Pediatrics
|July 8, 2025
PubMed

Insights

Primary caregivers of children with steroid-sensitive nephrotic syndrome (SSNS) face significant psychological distress, depression, and burden. Factors like disease severity and patient demographics are associated with these challenges.

Area of Science:

  • Pediatric Nephrology
  • Psychology
  • Caregiver Support

Background:

  • Steroid-sensitive nephrotic syndrome (SSNS) is a common kidney disease in children.
  • Caregiver well-being is crucial for managing chronic childhood illnesses.

Purpose of the Study:

  • To assess psychological distress, depression, and burden in caregivers of children with SSNS.
  • To explore associations between these factors and disease severity or demographics.

Main Methods:

  • Utilized General Health Questionnaire-12, Beck Depression Inventory, and Zarit Burden Interview-6 for assessment.
  • Included 60 primary caregivers of children aged 6 months to 15 years with SSNS.

Main Results:

  • High prevalence of severe depression (38.3%), psychological distress (30%), and caregiver burden (61.7%).
  • Steroid-dependent nephrotic syndrome (SDNS) and longer disease duration correlated with distress.
  • Identified risk factors for depression and burden including child's age, gender, disease subtype, treatment intensity, and hospitalization history.

Conclusions:

  • Caregivers of children with SSNS experience substantial psychological distress, depression, and financial burden.
  • Disease severity and specific demographic factors significantly impact caregiver mental health and burden.
Abstract

Keywords:
ChildFamilyKidneyMental healthPsychology

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