Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electrocardiographic changes in serious decompression sickness.

D R Leitch, J M Hallenbeck

    Aviation, Space, and Environmental Medicine
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Insights into cytoprotection from ground squirrel hibernation, a natural model of tolerance to profound brain oligaemia.

    Biochemical Society transactions·2006
    Same author

    Elevated pro-inflammatory CD4+CD28- lymphocytes and stroke recurrence and death.

    Neurology·2004
    Same author

    ICP monitoring following bilateral carotid occlusion in GFAP-null mice.

    Acta neurochirurgica. Supplement·2002
    Same author

    Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: a bedside-to-bench study.

    Stroke·2001
    Same author

    Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

    Molecular and cellular biology·2001
    Same author

    Mechanisms for increased levels of phosphorylation of elongation factor-2 during hibernation in ground squirrels.

    Biochemistry·2001
    Same journal

    Goodbye to ASEM.

    Aviation, space, and environmental medicine·2014
    Same journal

    AsMA - a worldwide organization.

    Aviation, space, and environmental medicine·2014
    Same journal

    This month in aerospace medicine history.

    Aviation, space, and environmental medicine·2014
    Same journal

    You're the flight surgeon: hypogonadism.

    Aviation, space, and environmental medicine·2014
    Same journal

    You're the flight surgeon: fatigue.

    Aviation, space, and environmental medicine·2014
    Same journal

    Manned-unmanned teaming: expanding the envelope of UAS operational employment.

    Aviation, space, and environmental medicine·2014
    See all related articles

    Electrocardiographic changes in dogs with spinal cord decompression sickness (DCS) indicate right heart strain, myocardial ischemia, and arrhythmias. Compression therapy did not always resolve these cardiac effects, suggesting further investigation is needed.

    Area of Science:

    • Veterinary Cardiology
    • Canine Physiology
    • Hyperbaric Medicine

    Background:

    • Spinal cord decompression sickness (DCS) can cause significant physiological disturbances.
    • Electrocardiographic (ECG) abnormalities have been anecdotally reported in DCS.
    • The cardiac implications of DCS in canines require further elucidation.

    Purpose of the Study:

    • To describe and analyze electrocardiographic (ECG) changes in dogs with spinal cord decompression sickness (DCS).
    • To correlate ECG findings with concurrent physiological events during DCS.
    • To explore potential mechanisms underlying cardiac dysfunction in canine DCS.

    Main Methods:

    • Continuous electrocardiographic monitoring was performed on 21 dogs diagnosed with spinal cord DCS.

    Related Experiment Videos

  • Physiological parameters including blood pressure and indicators of pulmonary hypertension were recorded.
  • Therapeutic interventions, including compression therapy, were administered and their effects on ECG noted.

    • Main Results:

    • Observed ECG changes included P wave peaking, P-R depression (right heart strain), S-T segment/T wave abnormalities (myocardial ischemia), and ventricular arrhythmias (premature ventricular contractions to ventricular tachycardia).
    • Compression therapy did not consistently or rapidly normalize ECG findings.
    • Cardiac changes were associated with pulmonary hypertension, systemic hypertension/hypotension, and cerebral DCS.

    Conclusions:

    • ECG monitoring is crucial for assessing cardiac involvement in canine spinal cord DCS.
    • Potential etiologies include direct cardiac DCS, coronary gas embolism, and autonomic disturbances secondary to central nervous system DCS.
    • Routine ECG evaluation should be considered in the clinical management of DCS in dogs.