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IL-18 revives dysfunctional CAR-T cells

Yan-Ruide Li1, Yichen Zhu1, Lili Yang2

  • 1Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Trends in Cancer
|July 8, 2025
PubMed

Keywords:
CAR-T dysfunctioncancer therapychimeric antigen receptor (CAR)interleukin-18 (IL-18)superior antitumor efficacy

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