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Identification of the Novel HLA-DQA1*06:06 Allele Using Next-Generation Sequencing

Junhyup Song1, Jongseon Park1, Sunmi Jung2

  • 1Department of Laboratory Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.

HLA
|July 9, 2025
PubMed
Abstract

Keywords:
HLA‐DQA1*06:06HLAnew allelenext‐generation sequencing

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.