Related Experiment Video
Updated: Sep 16, 2025

The Immersive Cleveland Clinic Virtual Reality Shopping Platform for the Assessment of Instrumental Activities of Daily Living
Published on: July 28, 2022
Feasibility, acceptability, patient experience, and preliminary efficacy of a virtual reality guided imagery
Lauren Doan1, Marc Recasens2, Jessica Lake1
1Department of Science, Limbix Health Inc., San Francisco, CA, United States.
Objectives:
Guided imagery is a strategy utilized in chronic pain management by patients. Benefits are cumulative via ongoing application. Engagement via Virtual Reality (VR) is becoming more accessible as a strategy to enhance adherence, use and benefit of guided imagery. We conducted a preliminary investigation of the feasibility, acceptability, patient experience, and efficacy of the use of VR for patients with chronic pain to use at home.
Methods:
36 patients with Complex Regional Pain Syndrome or Low Back Pain were randomly assigned to VR or audio only guided imagery groups. Feasibility, acceptability and patient experience were rated by participants. Outcomes assessed at baseline and post-intervention were pain, mental and physical health, and mood.
Results:
Results indicate that the intervention was feasible and found acceptable by participants. The intervention also demonstrated promising preliminary efficacy based on self-reported within-group decreases in pain, depressive symptoms, anxiety symptoms and improvements in physical and mental functioning.
Conclusions:
The use of VR shows promise for enhancing the application and experience of guided imagery training with people who have chronic pain.

