Related Experiment Video
Updated: Sep 16, 2025

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
VOXEL-TO-BLADDER FULLNESS SENSATION
Arda Bayer1, Betsy H Salazar2, Kris Hoffman2
1Rice University, Houston, TX.
None:
Current medical diagnosis and treatment methods for neurogenic lower urinary tract dysfunction (NLUTD) disorders are constrained by our limited understanding of how a set of the complex neural circuits that regulate the LUT function. Identifying robust biomarkers for perceived bladder sensation could be key to advancing diagnostic and therapeutic modalities for NLUTD. In this work, we applied a transfer learning approach to infer bladder fullness sensation from functional magnetic resonance imaging (fMRI) data. While the proposed approach effectively represented fMRI scans in the embedding space, it did not predict bladder fullness sensation significantly better than random chance.
More Related Videos
06:36A Decentralized Ex Vivo Murine Bladder Model with the Detrusor Muscle Removed for Direct Access to the Suburothelium during Bladder Filling
Published on: November 28, 2019
09:17In Vivo Luminal Measurement of Distension-Evoked Urothelial ATP Release in Rodents
Published on: September 7, 2022
Related Concept Videos
Urinary Bladder
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
Anatomy of the Genitourinary System II: Bladder and Urethra
Nursing Assessment of the Genitourinary System II: Inspection and Palpation
Imaging Studies VI: Voiding Cystourethrography and Cystography
Urodynamic Studies: Uroflowmetry
The Micturition Reflex
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...