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Cardiac Troponin T Elevation Predicts Mortality in Hospitalized COVID-19 Patients
Katelyn A Bruno1,2, R Scott Wright3, Joshua Culberson1,2
1Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida.
Objective:
To evaluate if cardiac troponin values predict poor outcomes in COVID-19 patients across the range of patients of different sex and age.
Methods:
We examined high-sensitivity cardiac troponin T (hs-cTnT) levels in 1,050 severely ill hospitalized COVID-19 patients who had hs-cTnT data available and participated in the Expanded Access Program for convalescent plasma study during the first wave (April-August 2020) of the COVID-19 pandemic.
Results:
We observed a continuous relationship between hs-cTnT levels and mortality in hospitalized males and females with COVID-19. This finding was present regardless of sex or age.
Conclusion:
These data indicate the prognostic ability of hs-cTnT to predict mortality in hospitalized COVID-19 patients across all relevant patient groups.
Clinical Trials Registration Number:
NCT04338360.
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