Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automatic quantification of vertebral cancellous bone remodeling during aging.

F Prêteux, C Bergot, A M Laval-Jeantet

    Anatomia Clinica
    |January 1, 1985
    PubMed
    Summary

    Aging causes significant vertebral bone loss, particularly in women. Trabecular bone distribution shifts, with more weight-bearing structures and enlarged spaces in older adults, impacting spinal health.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [The basis of endoscopic stones recognition, a prospective monocentric study].

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2019
    Same author

    [Not Available].

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2015
    Same author

    [Not Available].

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2015
    Same author

    Multicentre European COMAC-BME study on the standardisation of bone densitometry procedures.

    Technology and health care : official journal of the European Society for Engineering and Medicine·2014
    Same author

    Numerical assessment of the effects of the axial variations of porosity and mineralisation on the elastic properties in the human femoral neck.

    Computer methods in biomechanics and biomedical engineering·2013
    Same author

    Anatomical distribution of the degree of mineralization of bone tissue in human femoral neck: impact on biomechanical properties.

    Bone·2012

    Area of Science:

    • Anatomy
    • Gerontology
    • Biomedical Engineering

    Background:

    • Vertebral spongy bone undergoes anatomical changes with age.
    • Understanding these age-related transformations is crucial for bone health research.

    Purpose of the Study:

    • To quantify age-related anatomical changes in vertebral spongy bone.
    • To analyze the distribution and morphology of trabeculae in aging lumbar vertebrae.

    Main Methods:

    • Automatic image analysis of microradiographs from normal lumbar vertebrae.
    • Quantitative assessment of 1 mm-thick sagittal slices from 52 autopsied individuals (24 men, 28 women, aged 35-96).

    Main Results:

    • Significant bone loss observed over four decades: 60% in women and 45% in men in the vertebral body center.
    • Age-related redistribution of trabeculae: weight-bearing trabeculae become significantly more numerous than transverse ones.
    • Elderly individuals exhibit enlarged intertrabecular spaces and an increased proportion of thinner trabeculae.

    Conclusions:

    • Aging leads to substantial bone loss and altered trabecular architecture in the lumbar spine.
    • These structural changes in aging bone may influence vertebral strength and fracture risk.
    • The study highlights significant sex-based differences in age-related bone loss and trabecular remodeling.

    Related Experiment Videos