Refractory anaphylactic shock to peanut ingestion in a pediatric patient requiring extracorporeal life support

Allison B Frederick1, Courtney Tresslar1, Joshua Arenth2

  • 1Division of Pediatric Surgery, Department of Surgery, Medical University of South Carolina, Charleston, SC, USA.

Perfusion
|July 9, 2025
PubMed

Insights

Extracorporeal life support (ECLS) effectively treated anaphylactic shock in a pediatric patient, demonstrating its feasibility in younger populations. This case offers a new approach for refractory anaphylaxis management in children.

Area of Science:

  • Pediatric Critical Care Medicine
  • Allergy and Immunology
  • Cardiopulmonary Support

Background:

  • Anaphylactic shock is a severe allergic reaction that can lead to respiratory failure and circulatory collapse.
  • Current guidelines suggest extracorporeal life support (ECLS) for refractory anaphylactic shock, but evidence is limited to adult populations.
  • Pediatric anaphylaxis management often requires specialized interventions when conventional treatments fail.

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