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Lower Cervical Chordomas: A Case Report and Differential Diagnosis
Yosita Muenkaew1, Artit Jinawath2, Wichit Cheewaruangroj1
1Department of Otolaryngology-Head & Neck Surgery, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Cancer Reports (Hoboken, N.J.)
|July 9, 2025
Summary
This case highlights a rare lower cervical chordoma presenting as a neck mass. Early detection and multidisciplinary treatment are crucial for managing this challenging diagnosis.
Area of Science:
- Oncology
- Neurosurgery
- Pathology
Background:
- Chordomas are rare tumors originating from notochord remnants, typically in the axial skeleton.
- Lower cervical spine chordomas are exceptionally uncommon, posing diagnostic challenges.
Observation:
- A 79-year-old male presented with a left-sided neck mass, an atypical presentation for a chordoma.
- Clinical, radiological, and histological evaluations, including biopsy and immunohistochemistry, confirmed a lower cervical chordoma.
Findings:
- Accurate diagnosis of cervical chordoma requires integrated imaging and histological confirmation.
- Surgical resection is the primary treatment, often supplemented by radiation therapy and chemotherapy for residual or recurrent disease.
Implications:
- Lower cervical chordomas presenting as neck masses represent a diagnostic enigma.
- Multidisciplinary approaches involving imaging, immunohistochemistry, and radiation therapy are essential for complex surgical excision.
- Long-term follow-up and prompt detection are vital for improved patient outcomes and reduced recurrence rates.
