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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Holter monitoring is a continuous electrocardiography (ECG) recording that tracks the heart's electrical activity over an extended period, generally 24 to 48 hours. This noninvasive diagnostic tool detects irregular heart rhythms that may not be captured during a standard ECG performed in a clinical setting.DeviceThe Holter monitor is a portable, small device connected to several electrodes on the patient's chest. These electrodes detect the heart's electrical signals and transmit them to the...
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Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
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Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
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Exploring Optimal Cardiac Electronic Implantable Devices Programming: Reducing Non-Actionable Alerts and Assessing

Mohamed A Mostafa1, George Bodziock1, Lindsey Cotten2

  • 1Department of Cardiology, Wake Forest School of Medicine, Winston Salem, North Carolina, USA.

Journal of Cardiovascular Electrophysiology
|July 9, 2025
PubMed
Summary
This summary is machine-generated.

Optimizing cardiac implantable electronic device (CIED) alerts significantly reduced non-actionable alerts (NAA) and alert fatigue. This strategy safely improved efficiency without increasing adverse events like stroke or sudden cardiac death.

Keywords:
AFNSVTdevice clinicimplantable cardiac devicesremote monitoring

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Cardiac implantable electronic devices (CIEDs) generate increasing remote data.
  • Excessive non-actionable alerts (NAAs) lead to alert fatigue among clinicians.
  • There is a need to optimize CIED alert parameters.

Purpose of the Study:

  • To minimize NAAs by optimizing CIED alert parameters.
  • To evaluate the impact of optimized alert parameters on clinical outcomes.
  • To reduce alert fatigue in patients with CIEDs.

Main Methods:

  • 536 participants with CIEDs were included.
  • 413 patients had CIEDs reprogrammed to censor specific atrial fibrillation (AF) and non-sustained ventricular tachycardia (NSVT) alerts.
  • NAAs were tracked pre- and post-reprogramming; ischemic stroke and sudden cardiac death (SCD) were assessed over follow-up.

Main Results:

  • Reprogramming significantly decreased NAAs (p < 0.001).
  • Ischemic stroke rates were similar between reprogrammed and control groups for AF alerts.
  • Sudden cardiac death incidence was lower in reprogrammed patients with NSVT alerts compared to controls.

Conclusions:

  • Guideline-based CIED alert parameter optimization significantly reduced NAA burden.
  • This approach did not increase adverse outcomes (stroke, SCD) in patients with device-detected AF or NSVT.
  • Optimizing CIED alerts can safely reduce data noise and improve clinical efficiency.