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Published on: May 11, 2015
Portopulmonary hypertension: diagnosis and preoperative management
David W Wang1, Akira Katayama1,2, Marianne M Ligon1
1Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Purpose Of Review:
Preoperative management of portopulmonary hypertension (PoPH) has been difficult to establish because the prevalence of PoPH is relatively low. In recent years, however, several studies have provided new insights into this area. This review outlines the diagnosis and preoperative management of PoPH in light of the latest findings.
Recent Findings:
In a recent retrospective study including 723 patients who underwent liver transplantation, preoperative evaluation of right ventricular systolic pressure on transthoracic echocardiography (TTE) was well correlated with mean pulmonary arterial pressure on right heart catheterization (RHC). TTE can play an important role for screening patients with a higher likelihood of pulmonary hypertension before undergoing more invasive diagnostic testing with RHC.
Summary:
Liver transplantation for patients with irreversible PoPH is contraindicated. Early diagnosis and appropriate therapeutic interventions in patients with PoPH are crucial to prevent disease progression and improve patient prognosis.
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