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Applying Large Language Models for Surgical Case Length Prediction.

Adhitya Ramamurthi1,2, Bhabishya Neupane3, Priya Deshpande4

  • 1Selig Hub for Surgical Data Science, Medical College of Wisconsin, Milwaukee.

JAMA Surgery
|July 9, 2025
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Summary
This summary is machine-generated.

Large language models (LLMs) can accurately predict surgical case duration, matching or surpassing current operating room scheduling methods. Fine-tuned LLMs offer a promising tool for improving OR efficiency using clinical notes.

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Area of Science:

  • Artificial Intelligence in Healthcare
  • Surgical Operations Management
  • Clinical Informatics

Background:

  • Accurate prediction of surgical case duration is crucial for efficient operating room (OR) management.
  • Inefficient scheduling leads to decreased patient and surgeon satisfaction and significant financial losses.

Purpose of the Study:

  • To assess the feasibility and accuracy of large language models (LLMs) in predicting surgical case length.
  • To compare LLM performance against existing surgical case duration estimation methods using unstructured clinical data.

Main Methods:

  • Retrospective analysis of 125,493 elective surgical cases from 2017-2023.
  • Eleven LLMs, including GPT-4, GPT-3.5, Mistral, Llama-3, and Phi-3, were evaluated, with fine-tuned variants of GPT-4 and GPT-3.5.
  • Prediction accuracy was based on mean absolute error (MAE) and percentage of predictions within 20% of actual duration.

Main Results:

  • Fine-tuned GPT-4 achieved the best performance (MAE 47.64 min, R2 0.61), comparable to current OR scheduling (MAE 49.34 min, R2 0.63).
  • Fine-tuned LLMs (GPT-4 and GPT-3.5) significantly outperformed current methods in prediction accuracy (46.12% and 46.08% vs 40.92%, P < .001).
  • Fine-tuned GPT-4 demonstrated strong performance in external validation (MAE 48.66 min, accuracy 46.0%).

Conclusions:

  • Fine-tuned LLMs can predict surgical case length with accuracy comparable to or exceeding current institutional methods.
  • LLMs show potential for enhancing operating room efficiency through improved case length prediction.
  • Utilizing existing clinical documentation with LLMs offers a novel approach to surgical scheduling optimization.