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![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Visible-Light-Induced Catalyst-Free Three-Component Reaction of α-Hydroxy Ketones, Styrenes, and 4-Cyanopyridine
Huiying Zeng1,2, Renqin Zhan1, Baichuan Zhu1
1The State Key Laboratory of Natural Product Chemistry, and the College of Chemistry and Chemical Engineering, Lanzhou University, 222 Tianshui Road, Lanzhou, 730000, People's Republic of China.
Abstract:
A visible-light-induced, transition-metal- and photosensitizer-free three-component acylpyridylation of styrenes is presented. In this strategy, α-hydroxy ketones play a triple role: they act as visible-light-activated photosensitizers, acylation reagents, and reductants. This approach does not require transition-metals, external photosensitizers, or reductive reagent, demonstrating high efficiency, mild reaction conditions, and robust tolerance to various functional groups.
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