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Published on: February 9, 2021
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Infrared spectroscopic analysis of urinary stone composition
1Departamento de Medicina de Rehabilitación, Hospital 940 de la Fuerza Conjunta de Apoyo Logístico del Ejército Popular de Liberación de China, Lanzhou, China.
Actas Urologicas Espanolas
|July 9, 2025
Summary
Urinary stones in Lanzhou are predominantly mixed-type, with calcium oxalate and carbonate apatite being most common. Stone composition varies significantly by patient age and gender, informing clinical prevention strategies.
Area of Science:
- Urology
- Nephrology
- Medical Chemistry
Background:
- Urinary stone disease remains a significant health concern globally.
- Understanding the specific composition of urinary stones is crucial for effective management and prevention.
- Regional variations in stone composition necessitate localized epidemiological studies.
Purpose of the Study:
- To characterize the composition of urinary stones in the Lanzhou region.
- To identify demographic differences in stone composition based on gender and age.
- To provide a data-driven reference for clinical prevention and treatment strategies.
Main Methods:
- Analysis of urinary stone composition from 1284 patients in Lanzhou.
- Statistical analysis to determine differences in stone component distribution across genders and age groups.
- Evaluation of stone types, including single and mixed compositions.
Main Results:
- Mixed stone compositions were most prevalent (79.0%), with calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite being the most frequent combination (35%).
- Calcium oxalate stones were more common in the 18-60 age group, while the proportion of patients over 60 with stones was higher than in other groups.
- Significant gender-based differences were observed, with higher rates of apatite carbonate and magnesium ammonium phosphate hexahydrate in female patients.
Conclusions:
- Urinary stones in Lanzhou are predominantly mixed, with specific combinations like calcium oxalate monohydrate + calcium oxalate dihydrate + carbonate apatite being most common.
- Stone composition exhibits significant variations based on patient gender and age group.
- These findings underscore the importance of tailored clinical approaches for urinary stone prevention and treatment in the Lanzhou area.
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