Clinical profile and risk factors identified in patients with renal cancer in Mexican population
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View abstract on PubMed
Summary
This summary is machine-generated.Age over 50 is a risk factor for advanced renal cell carcinoma (RCC) stages, while obesity may lower this risk. Common symptoms include flank pain and hematuria.
Area Of Science
- Urology
- Oncology
- Nephrology
Background
- Renal cell carcinoma (RCC) is a significant global health concern, more prevalent in men and older individuals.
- Classic symptoms are rare; surgical interventions like nephrectomy carry potential complications.
Purpose Of The Study
- To determine the clinical characteristics and risk factors associated with renal cell carcinoma (RCC).
- To analyze the relationship between patient demographics, comorbidities, and disease presentation and stage.
Main Methods
- An observational, cross-sectional study analyzed 83 surgically treated renal cell carcinoma (RCC) patients from January 2020 to June 2023.
- Demographic, clinical, and comorbidity data were assessed against TNM staging, histology, morbidity, and mortality outcomes.
Main Results
- The study included 83 patients (57% male, mean age 59.2 years).
- Hypertension and obesity were common comorbidities (44.6% each). Flank pain (44.6%) and hematuria (27.7%) were leading symptoms.
- Age >50 years correlated with advanced RCC stages (OR 5.744), whereas obesity showed a protective association (OR 0.220).
Conclusions
- Age over 50 is identified as a risk factor for advanced renal cell carcinoma (RCC).
- Obesity appears to be associated with a reduced risk of advanced disease stages.
- Flank pain and hematuria are frequent clinical manifestations of RCC, unlike abdominal mass.
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