[Effect of changes in blood glucose concentration on the standing potential of the rabbit eye]

The paper deals with the study of the influence of changes of glucose blood concentration in rabbits on the standing potential of the eye, which reflects the functioning of the retinal pigment epithelium and photoreceptors. Recordings of the electrooculogram (EOG), determination of glucose blood level and ophthalmoscopic and histological examinations of the eye were performed in 48 rabbits. Short-term increase of glucose concentration was accompanied by the increase in the standing potential and Arden EOG ratio, with hypoglycemia evoking the opposite effect. A long-term (4 month) hyperglycemia was accompanied by the reversible decrease of both parameters studied. No ophthalmoscopic and histological changes were observed.