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Updated: Sep 16, 2025
Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Development of a deep learning-based MRI diagnostic model for human Brucella spondylitis
Binyang Wang1, Jinquan Wei2, Zhijun Wang3
1Ningxia Institute of Clinical Medicine, The Third Clinical Medicine College, People's Hospital of Ningxia Hui Autonomous Region, Ningxia Medical University, Zhengyuan Street 301, Yinchuan, 750002, China.
Introduction:
Brucella spondylitis (BS) and tuberculous spondylitis (TS) are prevalent spinal infections with distinct treatment protocols. Rapid and accurate differentiation between these two conditions is crucial for effective clinical management; however, current imaging and pathogen-based diagnostic methods fall short of fully meeting clinical requirements. This study explores the feasibility of employing deep learning (DL) models based on conventional magnetic resonance imaging (MRI) to differentiate BS and TS.
Methods:
A total of 310 subjects were enrolled in our hospital, comprising 209 with BS, 101 with TS. The participants were randomly divided into a training set (n = 217) and a test set (n = 93). And 74 with other hospital was external validation set. Integrating Convolutional Block Attention Module (CBAM) into the ResNeXt-50 architecture and training the model using sagittal T2-weighted images (T2WI). Classification performance was evaluated using the area under the receiver operating characteristic (AUC) curve, and diagnostic accuracy was compared against general models such as ResNet50, GoogleNet, EfficientNetV2, and VGG16.
Results:
The CBAM-ResNeXt model revealed superior performance, with accuracy, precision, recall, F1-score, and AUC from 0.942, 0.940, 0.928, 0.934, 0.953, respectively. These metrics outperformed those of the general models.
Conclusions:
The proposed model offers promising potential for the diagnosis of BS and TS using conventional MRI. It could serve as an invaluable tool in clinical practice, providing a reliable reference for distinguishing between these two diseases.
