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Updated: Sep 16, 2025
02:28
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
498
Global Guidelines for Psoriatic Arthritis Management: A Comparative Analysis.
Shikha Singla1, Parjanya Bhatt2, Enrique Roberto Soriano
1Medical College of Wisconsin, Milwaukee, WI.
Summary
Global psoriatic arthritis (PsA) guidelines recommend treat-to-target strategies. However, significant differences exist in treatment sequencing for biologic and targeted disease-modifying antirheumatic drugs (DMARDs), enthesitis, and dactylitis management.
Area of Science:
- Rheumatology
- Immunology
- Clinical Guideline Development
Background:
- Psoriatic arthritis (PsA) is a complex, immune-mediated inflammatory disease with multisystem involvement.
- Treatment decisions for PsA are challenging due to its heterogeneous nature.
- Comparative analysis of global guidelines is crucial for refining PsA management strategies.
Purpose of the Study:
- To comparatively analyze the latest global psoriatic arthritis (PsA) management guidelines.
- To highlight differences in approaches to treating various PsA domains.
- To inform and guide future PsA treatment strategies.
Main Methods:
- Systematic review of major international PsA management guidelines.
- Inclusion of guidelines from 2018 to 2024 from key rheumatology associations.
- Comparative analysis of treatment recommendations across different PsA domains.
Main Results:
- Unanimous recommendation for a treat-to-target strategy in active PsA.
- Divergence in treatment sequencing for biologic and targeted disease-modifying antirheumatic drugs (DMARDs).
- Variations noted in managing enthesitis and dactylitis; comorbidities are key for disease control.
Conclusions:
- Global guidelines present diverse management strategies for psoriatic arthritis (PsA).
- Future recommendations may incorporate novel therapeutic targets.
- Optimizing PsA care requires addressing comorbidities and tailoring treatments to specific disease domains.
Keywords:
American College of RheumatologyBritish Society of RheumatologyEuropean Alliance of Associations for RheumatologyGroup for Research and Assessment of Psoriasis and Psoriatic ArthritisPan American League of Associations for Rheumatologydomains of psoriatic arthritisguidelinespsoriatic arthritis
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