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Updated: Sep 16, 2025

Murine Isolated Heart Model of Myocardial Stunning Associated with Cardioplegic Arrest
Published on: August 6, 2015
Assessing myocardial stunning during continuous renal replacement therapy in critically ill patients
Hajar Berrichi1,2, Safaa Bekkaoui1,2, Younes Oujidi1,2
1Department of Anaesthesiology and Intensive Care Unit, Mohammed VI University Hospital, Oujda, Morocco.
Introduction:
Myocardial stunning, a temporary reduction in cardiac contractility, is well-recognized in chronic hemodialysis patients but less studied in critically ill patients undergoing continuous renal replacement therapy (CRRT).
Methods:
A prospective observational 11-month study included 38 intensive care unit (ICU) patients with acute kidney injury at Mohammed V University Hospital. Myocardial stunning was evaluated using echocardiographic parameters such as global longitudinal strain and left ventricular ejection fraction.
Results:
Myocardial stunning was observed in 60.5% of patients. It was strongly associated with increased vasopressor requirements, longer ICU stays, and higher mortality (47.8% vs. 6.7%).
Conclusion:
The high incidence of myocardial stunning in critically ill patients undergoing CRRT highlights the need for vigilant cardiac monitoring and targeted interventions to improve patient outcomes.
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