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Updated: Sep 16, 2025
Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Microbiological assessment of silver nanoparticles versus minocycline
Nalini M S1, Arvind Raghunath1, Sravani Bontu1
1Department of Periodontology, Raja Rajeswari Dental College and Hospital, Bangalore, Karnataka, India.
Abstract:
Evaluation of 0.02% silver nanoparticle (AGNP) gel and 2% minocycline gel as adjuncts to scaling and roots planning (SRP) in chronic periodontitis is of interest. Hence, 30 patients with 90 sites were divided into three groups: SRP alone, SRP + AGNP and SRP + minocycline. Clinical parameters improved significantly in all groups at 3 months (p < 0.001). AGNP and minocycline showed superior outcomes to SRP alone, with no significant difference between them. Thus, AGNP gel is as effective as minocycline and may serve as a promising adjunctive therapy.
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