Related Experiment Video
Updated: Sep 16, 2025

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
Published on: April 21, 2022
Thermal ocular injury associated with retinal necrosis and vitreous inflammation: a case report
Ruiping Gu1,2,3,4, Yue Guo1,2,3,4,5, Boya Lei1,2,3,4
1Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China.
Background:
A case of thermal ocular injury associated with retinal necrosis and vitreous inflammation is reported.
Case Presentation:
A 53-year-old man's right eye was hit by a heated screw, which embedded directly into the nasal orbit. Two weeks after the foreign body was removed, serious vitreous inflammation and a large yellow-white lesion on the nasal peripheral retina, which resembled a subretinal abscess, were observed. Endophthalmitis could not be ruled out and vitrectomy was performed. During vitrectomy, we identified the yellow-white lesion as retinal necrosis and edema, with localized retinal detachment within the lesion. After surgery, there was significant macular atrophy with poor vision.
Conclusion:
Thermal retinal burns must be differentiated from infectious endophthalmitis to ensure timely anti-inflammatory treatment.

