Related Experiment Video
Updated: Sep 16, 2025

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
An Unusual Case of Fusarium Endophthalmitis: The Importance of Early Diagnosis and Treatment
Jeevakanthi Rajendran1, Jia Wei Chai1, Pey Yih Ng2
1Medicine, Hospital Sultanah Nora Ismail, Batu Pahat, MYS.
Abstract:
Fusarium endophthalmitis is a rare but devastating ocular infection, often associated with trauma or systemic immunosuppression. It is caused by Fusarium species, a group of filamentous fungi that are widely found in soil and plant material. The infection is characterized by rapid progression and poor visual prognosis if not promptly treated. We present an interesting case of Fusarium endophthalmitis in an immunocompetent elderly male with no prior ocular illness. Early diagnosis and prompt administration of antifungal therapy, including intravitreal amphotericin B and systemic voriconazole, along with surgical intervention, contributed to a favorable clinical outcome.
Insights
Fusarium endophthalmitis, a severe eye infection, can occur even in healthy individuals. Prompt diagnosis and combined antifungal therapy with surgery led to a positive outcome in an immunocompetent patient.
Area of Science:
- Ophthalmology
- Mycology
Background:
- Fusarium endophthalmitis is a rare fungal eye infection.
- It is typically linked to trauma or weakened immune systems.
Observation:
- A case of Fusarium endophthalmitis occurred in an elderly male without prior eye issues or immunosuppression.
- The patient was otherwise healthy.
Findings:
- Early diagnosis was crucial for successful treatment.
- Combined therapy included intravitreal amphotericin B, systemic voriconazole, and surgery.
Implications:
- This case highlights that Fusarium endophthalmitis can affect immunocompetent individuals.
- Aggressive, multimodal treatment can achieve favorable outcomes in complex fungal endophthalmitis cases.
Related Concept Videos
Glaucoma: Overview
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Fungal Phylum Microsporidia

