Buschke-Löwenstein Tumour: Surgical Management and Literature Review of an Unusual Disease

Buschke-Löwenstein tumours (BLTs) are rare, sexually transmitted lesions associated with human papillomavirus (HPV) infections that primarily affect the perineal and genito-anal regions. Surgical excision is the standard treatment; however, management is often complicated by the tumour's local invasiveness, disease progression, variable treatment response, and high recurrence rates. Wound healing is especially challenging due to the proximity to perineal structures, increasing the risk of contamination and infection. We present the case of a man in his 50s with a large, circumferential anal BLT and a background of immunosuppression from prednisolone and mycophenolate treatment. This case highlights the complexities of managing BLTs and demonstrates surgical strategies, including reconstruction and diverting colostomy, to optimise both cosmetic and functional outcomes.