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Colonic Diaphragm Disease Induced by Chronic Non-steroidal Anti-inflammatory Drug (NSAID)-Use Requiring Multiple
Hasan Jaber1, Fawzi Elias1, Nader Al Souky1
1Internal Medicine, University of Kansas School of Medicine, Wichita, USA.
Cureus
|July 10, 2025
Summary
Chronic NSAID use can cause colonic diaphragm disease, a rare condition leading to gastrointestinal issues. Advanced endoscopic interventions are crucial for managing these complex NSAID-induced strictures.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain and inflammation.
- NSAID-induced colonic diaphragm disease is an infrequent but serious gastrointestinal complication.
Observation:
- A 51-year-old male with a history of chronic NSAID use presented with abdominal pain, weight loss, and GI bleeding.
- Diagnostic imaging and endoscopy identified a colonic stricture indicative of diaphragm disease.
Findings:
- The colonic stricture was short and benign in appearance.
- The patient underwent multiple endoscopic procedures, including stent placement and balloon dilation, to address the obstruction.
Implications:
- Recognizing NSAID-induced colonic pathology is vital for timely diagnosis and treatment.
- Advanced endoscopic techniques offer effective management options for NSAID-induced colonic strictures.
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