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Published on: August 26, 2014
Colonic Diaphragm Disease Induced by Chronic Non-steroidal Anti-inflammatory Drug (NSAID)-Use Requiring Multiple
Hasan Jaber1, Fawzi Elias1, Nader Al Souky1
1Internal Medicine, University of Kansas School of Medicine, Wichita, USA.
Abstract:
Non-steroidal anti-inflammatory drug (NSAID)-induced colonic diaphragm disease is an uncommon yet significant cause of gastrointestinal symptoms. We present a case of a 51-year-old male with chronic NSAID use who developed abdominal pain, weight loss, and gastrointestinal bleeding. Imaging and endoscopy revealed a short, benign-appearing stricture in the ascending colon consistent with diaphragm disease. The patient required multiple endoscopic interventions, including lumen-apposing metal stent placement and balloon dilation, to relieve the obstruction. This case underscores the importance of recognizing NSAID-induced colonic pathology and highlights the role of advanced endoscopic techniques in managing complex strictures.
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