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Related Experiment Videos

Gallbladder visualisation following paediatric cardioangiography with Hexabrix.

J E Gillespie, A Gholkar, S Gupta

    The British Journal of Radiology
    |June 1, 1985
    PubMed
    Summary

    Hexabrix (meglumine/sodium ioxaglate) contrast media allowed clear gallbladder visualization in 64% of pediatric patients. This contrasts with older agents and suggests dose is key, not kidney function.

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    Area of Science:

    • Radiology
    • Pediatric Imaging
    • Contrast Media

    Background:

    • Gallbladder visualization on radiographs after cardioangiography is typically uncommon.
    • Conventional uro-angiographic contrast media (diatrizoate, iothalamate) rarely opacify the gallbladder.
    • Gallbladder opacification with older contrast agents is often linked to renal impairment.

    Purpose of the Study:

    • To assess gallbladder visualization following cardioangiography with Hexabrix in children.
    • To determine if Hexabrix differs from conventional contrast media regarding gallbladder opacification.
    • To investigate factors influencing gallbladder visualization after contrast administration.

    Main Methods:

    • Fifty pediatric patients underwent upper abdominal radiography 24 hours post-cardioangiography.

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  • Contrast agent used was Hexabrix (meglumine/sodium ioxaglate).
  • Patients were assessed for gallbladder visualization and evidence of renal impairment.

    • Main Results:

    • The gallbladder was clearly visualized in 32 out of 50 patients (64%).
    • Gallbladder visualization occurred without clinical or radiographic signs of renal impairment.
    • Total contrast dose appeared to be the primary factor influencing visualization.

    Conclusions:

    • Hexabrix facilitates significant gallbladder opacification in pediatric patients undergoing cardioangiography.
    • This effect is independent of renal impairment, unlike with older contrast agents.
    • Contrast dose is a key determinant for Hexabrix-induced gallbladder visualization.