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Incentivized Community-Based Syphilis Screening: Uptake, Yield, and Cost
Meghan Curry O'Connell1, Tinka Duran1, Sarah Shewbrooks1
1From the Great Plains Tribal Leaders Health Board, Great Plains Tribal Epidemiology Center.
Sexually Transmitted Diseases
|July 10, 2025
Summary
Community syphilis testing in South Dakota found a 5.3% prevalence of undiagnosed infections. Incentives increased access to vital screening and treatment for American Indian/Alaska Native populations.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Community Health Interventions
Background:
- Syphilis rates are alarmingly high and increasing among American Indian/Alaska Native (AI/AN) communities, especially affecting women and infants.
- Urgent interventions are needed to provide syphilis testing and timely treatment to sexually active AI/AN populations.
Purpose of the Study:
- To implement and evaluate a community-based syphilis screening program in Rapid City, South Dakota.
- To assess the prevalence of undiagnosed syphilis and the effectiveness of incentives in a target population.
Main Methods:
- A partnership between the Great Plains Tribal Epidemiology Center and a local healthcare facility offered free community-based syphilis, HIV, and HCV testing from December 2022 to June 2024.
- Participants received cash incentives for undergoing testing.
- Fifteen testing events were conducted, with 1434 unique individuals tested.
Main Results:
- A syphilis prevalence of 5.3% (76/1434) was identified among previously undiagnosed individuals, with 67.1% being female.
- Treatment was provided to 80.3% of those diagnosed with syphilis within an average of 36 days.
- The cost per test was $88, and the cost to identify a new case was $2,079.
Conclusions:
- Community-based screening effectively identified a high prevalence of undiagnosed syphilis.
- Incentives played a crucial role in encouraging community member participation in screening services.
- Collaborative, community-centered approaches are beneficial for syphilis diagnosis and treatment but require sustained resources.
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