Related Experiment Video

Updated: Sep 16, 2025

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction
08:35

Oxygenation-sensitive Cardiac MRI with Vasoactive Breathing Maneuvers for the Non-invasive Assessment of Coronary Microvascular Dysfunction

Published on: August 17, 2022

2.5K

Identification of risk factors in myocardial infarction with non-obstructive coronary arteries

Aydın Dursun1, Hakan Guven2, Mehmet Cem Basel1

  • 1Mudanya University, VM Medical Park Hospital, Department of Cardiology - Bursa, Türkiye.

Revista Da Associacao Medica Brasileira (1992)
|July 10, 2025
PubMed

Insights

Smoking and hypertension are key risk factors for myocardial infarction with non-obstructive coronary arteries (MINOCA). Vitamin D deficiency is also significantly associated with MINOCA, with myocardial bridge being a common cause.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Vascular Biology

Background:

  • Acute coronary syndrome (ACS) encompasses various cardiac events.
  • Myocardial infarction with non-obstructive coronary arteries (MINOCA) presents a diagnostic challenge.
  • Identifying risk factors and causes of MINOCA is crucial for patient management.

Purpose of the Study:

  • To identify risk factors and potential causes of MINOCA in ACS patients.
  • To compare nutrient levels (Vitamin D, B12, folate) in MINOCA patients versus controls.
  • To analyze clinical, laboratory, and imaging findings in MINOCA.

Main Methods:

  • Retrospective case series of 195 MINOCA patients from 3,107 ACS cases (Jan 2019-Dec 2023).
  • Analysis of clinical characteristics, risk factors, and laboratory results.
  • Comparison of vitamin D, homocysteine, folate, and vitamin B12 levels with controls.

Main Results:

  • MINOCA accounted for 6.28% of ACS cases; 83% were male, mean age 53.9 years.
  • Prominent risk factors included smoking (70%), hypertension (45%), and diabetes (33%).
  • Myocardial bridge was the most common cause (11.2%); lower Vitamin D, B12, and folate levels were observed in MINOCA patients.

Conclusions:

  • Smoking and hypertension are significant risk factors for MINOCA.
  • Myocardial bridge is a frequent cause of MINOCA.
  • Vitamin D deficiency is associated with MINOCA, highlighting potential nutritional links.
Abstract

More Related Videos

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

4.0K
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

15.4K

Related Concept Videos

Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
63
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.4K
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
38
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
40
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
80
Angina II: Classification01:27

Angina II: Classification

Angina, also known as angina pectoris, is a chest pain resulting from diminished blood flow to the heart muscle and is often a symptom of coronary artery disease. Angina presents several variants with distinctive attributes, etiologies, and therapeutic approaches. The main types of angina include stable, unstable, variant (Prinzmetal's), microvascular, intractable, and silent ischemia.Stable angina is caused by atherosclerosis, which leads to the formation of plaques that narrow the coronary...
44