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Factors associated with death from COVID-19 in traditional peoples and communities in Brazil
Sebastião Bruno Taveira Silva1, Audêncio Victor2,3, Ana Raquel Ernesto Manuel Gotine2
1Ministry of Health, Secretariat of Health Surveillance and Environment, General Coordination of Immunopreventable Diseases Surveillance (CGVDI), Brasília, DF, Brazil.
Insights
COVID-19 mortality in Brazil
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- COVID-19 disproportionately affects vulnerable populations in Brazil.
- Traditional communities face health disparities, increasing severe COVID-19 outcomes.
- Identifying mortality factors in these groups is crucial for targeted interventions.
Purpose of the Study:
- To identify factors associated with COVID-19 mortality.
- Focus on hospitalized patients from traditional communities in Brazil.
Main Methods:
- Cross-sectional study of COVID-19 hospitalizations (2021-2023).
- Data from the System of Epidemiological Surveillance of Influenza (SIVEP-Gripe).
- Logistic regression analysis of demographic, clinical, and comorbidity data.
Main Results:
- Male sex, older age, Black, and Indigenous ethnicity increased mortality risk.
- Dyspnea, low oxygen saturation, immunosuppression, and chronic renal disease were risk factors.
- Invasive ventilation (OR=19.4) posed the highest mortality risk.
Conclusions:
- Male sex, older age, race/color, severe respiratory symptoms, comorbidities, and invasive ventilation are key mortality predictors.
- Findings highlight the need for targeted health strategies for vulnerable populations.
- Reducing COVID-19 mortality in traditional communities requires focused public health efforts.
Introduction:
COVID-19 has disproportionately impacted vulnerable populations, including traditional communities in Brazil, who face socioeconomic and health disparities, increasing the risk of severe outcomes. This study aims to identify factors associated with mortality among hospitalized COVID-19 patients from traditional communities in Brazil.
Methods:
This cross-sectional study analyzed data from the System of Epidemiological Surveillance of Influenza (SIVEP-Gripe) on hospitalizations for COVID-19 between 2021 and 2023. Individuals from traditional communities were included. The variables analyzed included demographic characteristics, clinical symptoms, comorbidities, and the need for hospital support. Logistic regressions were performed to assess associations with mortality, considering p < 0.05 significant.
Results:
Of the 7,101 cases analyzed, males showed a higher risk of death (OR = 1.39; 95% CI: 1.18-1.63). Among ethnic groups, blacks presented with an OR = 2.92 (95% CI: 1.68-5.08) and indigenous, OR = 2.25 (95% CI: 1.73-2.94). Older age increased the risk, with OR = 6.57 (95% CI: 2.16-28.5) for ages 60-79 and OR = 12.8 (95% CI: 4.18-55.8) for ≥80 years. Dyspnea (OR = 2.16; 95% CI: 1.77-2.65) and low saturation (OR = 2.13; 95% CI: 1.78-2.55) were associated with death, while loss of taste was protective (OR = 0.62; 95% CI: 0.51-0.75). Immunosuppression (OR = 2.14; 95% CI: 1.23-3.79) and chronic renal disease (OR = 1.64; 95% CI: 1.10-2.46) increased the risk. Patients on invasive ventilation had the highest risk of death (OR = 19.4; 95% CI: 15.2-25.0), followed by non-invasive ventilation (OR = 2.65; 95% CI: 2.18-3.23) and ICU (OR = 2.15; 95% CI: 1.85-2.49).
Conclusion:
Risk factors for mortality among hospitalized patients from traditional communities include male sex, older age, race/color, severe respiratory symptoms, comorbidities, and the need for invasive ventilation. These findings reinforce the importance of targeted health strategies to reduce the risk of mortality in these vulnerable populations.
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