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Updated: Aug 28, 2026

Natural Killer NK and CAR-NK Cell Expansion Method using Membrane Bound-IL-21-Modified B Cell Line
Published on: February 8, 2022
Extranodal natural killer/T-cell lymphoma with lung involvement in a young adult with suspected mosquito bite
Mariko Higa1, Eriko Atsumi2, Hironobu Hoshino3
1Division of Pulmonary Medicine, National Hospital Organization (NHO) Okinawa Hospital, 3-20-14 Ganeko, Ginowan, Okinawa, 901-2214, Japan.
Abstract:
A young adult with suspected pulmonary lymphoma was diagnosed with extranodal natural killer/T-cell lymphoma (ENKTL). The patient had a history of possible mosquito bite hypersensitivity (MBH), suggesting a potential association between MBH and ENKTL. Although ENKTL typically affects middle-aged adults, it has rarely been reported in children with MBH or chronic active Epstein-Barr virus (EBV) disease. This case highlights the challenges of obtaining pathological confirmation from small biopsy samples of pulmonary ENKTL. Detailed history taking and EBV DNA testing may aid in diagnosis, particularly in younger patients.

