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Updated: Sep 16, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

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A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner

Aude Sylvain1, Natacha Stoehr1, Fupeng Ma2

  • 1Novartis Biomedical Research, Basel, Switzerland.

Cell Chemical Biology
|July 10, 2025
PubMed

Keywords:
CRBNNEK7NLRP3 inflammasomeinflammationmolecular glue degrader

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