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Updated: May 2, 2026

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Multi-protein-triggered, aptamer-tethered auto-cycling proximity recorder in formalin-fixed paraffin-embedded tissues

Xiaofang Zheng1, Daikun Zheng2, Linfeng Zheng3

  • 1Zhejiang Cancer Hospital, Key Laboratory of Zhejiang Province for Aptamers and Theranostics, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, PR China; Chongqing Key Laboratory of Development and Utilization of Genuine Medicinal Materials in Three Gorges Reservoir Area, Chongqing Engineering Research Center of Antitumor Natural Drugs, Chongqing Three Gorges Medical College, Chongqing 400030, PR China.

Analytical Biochemistry
|July 10, 2025
PubMed

Keywords:
AptamerAuto-cycling proximity recordingClinical FFPE breast cancer tissuesFluorescence imagingSpatial proximity

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