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Studies on the identification of genetic risk for heritable colon cancer
Cancer Detection and Prevention
|January 1, 1985
Abstract:
The limitations of the assignment of genetic risk status for colon cancer based on pedigree data are known. The purpose of this paper is to present two approaches being evaluated for the identification of genetic predisposition for colon cancer: in vivo studies on colonic mucosa and in vitro studies on dermal fibroblasts derived from high- and low-risk individuals.