A Rare Synchronous Existence of Warthin's Tumour and Oral Cancer: A systematic review

Oral squamous cell carcinoma (OSCC) is a common malignancy, while Warthin's tumour (WT) is a benign salivary gland neoplasm, typically found in the parotid gland but rarely involving extra-parotid tissues. The synchronous occurrence of OSCC and extra-parotid WT is particularly unusual. Accurate identification of these pathologies is crucial, as their rare presentation can resemble metastasis in lymph nodes. This review systematically searched for case reports and series of synchronous WT and OSCC, including 13 papers having 17 cases. The quality of these cases was assessed using CARE guidelines. The findings described WT's histological features and location in patients with OSCC, with many cases involving cervical lymph nodes. Over 50% of the cases had a history of tobacco use. Follow-up showed no recurrence in the reported cases. Awareness of the synchronous occurrence of WT and OSCC can prevent overtreatment and misdiagnosis, improving patient management.