Related Experiment Video
Updated: Sep 16, 2025

Robotic-assisted Lateral Pancreaticojejunostomy for Chronic Pancreatitis
Published on: September 5, 2025
A Case of Mirizzi Syndrome with Pancreatic Divisum: A rare association
Divya Muthuvel1, Anita Soundarapandian1
1Department of Radiodiagnosis, Panimalar Medical College Hospital and Research Institute, Chennai, India.
Abstract:
Mirizzi syndrome (MS), a rare complication of gallstones, refers to extrahepatic biliary compression by calculus in the cystic duct or Hartman's pouch and is usually associated with cystic duct abnormalities. Its association with pancreatic divisum (PD) is infrequent, the most common complication of PD being recurrent pancreatitis. We report a 39-year-old female patient who presented to a department of general surgery in Chennai, India, in 2022 with acute abdominal pain. Magnetic resonance cholangiopancreaticography (MRCP) showed calculous cholecystitis with a calculus indenting the cystic duct, causing luminal narrowing of the common hepatic duct (type I), which was associated with type II PD. The association of MS with PD has been rarely described. PD may be one of the factors responsible for bile stasis leading to calculous cholecystitis and its complications. Knowledge of MS and its associations helps in early diagnosis and selection of appropriate treatment management.
Insights
Mirizzi syndrome, a rare gallstone complication, can occur with pancreatic divisum. This case highlights their infrequent association and potential link to bile stasis, aiding diagnosis.
Area of Science:
- Gastroenterology
- Hepatobiliary Surgery
Background:
- Mirizzi syndrome (MS) involves biliary compression from gallstones in the cystic duct or Hartman's pouch.
- Pancreatic divisum (PD) is a common congenital anomaly, typically causing recurrent pancreatitis.
Observation:
- A 39-year-old female presented with acute abdominal pain.
- MRCP revealed type I Mirizzi syndrome compressing the common hepatic duct and type II pancreatic divisum.
Findings:
- This case details the rare co-occurrence of Mirizzi syndrome and pancreatic divisum.
- The patient's presentation involved gallstone-induced biliary obstruction and a pancreatic duct anomaly.
Implications:
- Pancreatic divisum may contribute to bile stasis, increasing the risk of gallstone disease and Mirizzi syndrome.
- Recognizing this association is crucial for accurate diagnosis and effective treatment planning.
Related Concept Videos
Other Disorders of Digestive System
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Pancreas
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
Pancreatic Juice and Secretion
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...

