A Case of Mirizzi Syndrome with Pancreatic Divisum: A rare association

Divya Muthuvel1, Anita Soundarapandian1

  • 1Department of Radiodiagnosis, Panimalar Medical College Hospital and Research Institute, Chennai, India.

Insights

Mirizzi syndrome, a rare gallstone complication, can occur with pancreatic divisum. This case highlights their infrequent association and potential link to bile stasis, aiding diagnosis.

Area of Science:

  • Gastroenterology
  • Hepatobiliary Surgery

Background:

  • Mirizzi syndrome (MS) involves biliary compression from gallstones in the cystic duct or Hartman's pouch.
  • Pancreatic divisum (PD) is a common congenital anomaly, typically causing recurrent pancreatitis.

Observation:

  • A 39-year-old female presented with acute abdominal pain.
  • MRCP revealed type I Mirizzi syndrome compressing the common hepatic duct and type II pancreatic divisum.

Findings:

  • This case details the rare co-occurrence of Mirizzi syndrome and pancreatic divisum.
  • The patient's presentation involved gallstone-induced biliary obstruction and a pancreatic duct anomaly.

Implications:

  • Pancreatic divisum may contribute to bile stasis, increasing the risk of gallstone disease and Mirizzi syndrome.
  • Recognizing this association is crucial for accurate diagnosis and effective treatment planning.

Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.0K
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
166
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
131
Pancreas01:19

Pancreas

The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short...
1.2K
Pancreatic Juice and Secretion01:26

Pancreatic Juice and Secretion

Pancreatic juice is a clear fluid produced by the pancreas, containing water, salts, sodium bicarbonate, and enzymes vital for digestion in the small intestine. It helps break down large molecules, facilitating nutrient absorption.
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
1.5K
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
369