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Identifying genetic determinants of Mycobacterium tuberculosis acid growth arrest by transposon mutagenesis coupled

Claire Healy1, Thomas R Ioerger2, Sabine Ehrt3

  • 1School of Medicine, Trinity College Dublin, Dublin, Ireland.

Microbiology Resource Announcements
|July 11, 2025
PubMed

Keywords:
Mycobacterium tuberculosisacid stresstransposon library

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Transposons01:24

Transposons

Transposons, or "jumping genes," are small mobile genetic elements (MGEs) that range from 700 to 40,000 base pairs in length. They are found in all organisms and can move within the same chromosome or transfer to different chromosomes. In some cases, transposons can also jump between different host DNA molecules, such as plasmids or viruses, contributing to genetic variability.Barbara McClintock first discovered these mobile genetic elements in the 1940s while studying maize genetics, and she...
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