D-amino acid metabolic versatility as a common adaptive strategy in the Mariana Trench microbiome
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View abstract on PubMed
Summary
This summary is machine-generated.Microbes in deep-sea trenches can metabolize D-amino acids (D-AAs), challenging the idea that they are always recalcitrant. This suggests D-AA turnover is environmentally dependent in the hadal zone.
Area Of Science
- Marine microbiology
- Biogeochemistry
- Molecular ecology
Background
- Hadal trenches host microbial communities crucial for recalcitrant dissolved organic matter (RDOM) turnover.
- The role of microbes in D-amino acid (D-AA) cycling within deep-sea RDOM remains largely unexplored.
- D-AAs are significant components of deep-sea RDOM and indicators of organic matter recalcitrance.
Purpose Of The Study
- To investigate the metabolic potential of D-AAs in the hadal zone.
- To identify microbial taxa involved in D-AA metabolism.
- To understand the ecological significance of D-AA turnover in extreme deep-sea environments.
Main Methods
- Curated a D-AA functional gene database for metagenomic analysis.
- Identified D-AA anabolic and catabolic genes in Mariana Trench water column and sediment samples.
- Analyzed bacterial and archaeal genomes for D-AA gene presence.
- Examined the correlation between D-AA genes and central carbon metabolism/ammonia oxidation genes.
Main Results
- Identified diverse D-AA metabolic genes correlated with central carbon and ammonia oxidation pathways.
- Found that 93.6% of recovered microbial genomes possess D-AA functional genes.
- Discovered glutamate racemase in ammonia-oxidizing archaea, suggesting D-glutamate integration into hadal biogeochemical cycles.
- Observed increased D-AA production and degradation potential with water depth, higher in seawater than sediment.
Conclusions
- D-AA metabolism is a prevalent ecological function in the deepest ocean, driven by diverse microbial taxa.
- The ubiquitous presence of glutamate racemase in ammonia-oxidizing archaea highlights their role in hadal D-glutamate cycling.
- Increased D-AA turnover with depth suggests an adaptive response to extreme hadal conditions, challenging the notion of constant D-AA recalcitrance.
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