Intracranial Collision Tumor: Coexistence of Pituitary Adenoma and Craniopharyngioma

A collision tumor refers to the occurrence of 2 or more distinct types of tumors developing in the same anatomic location. Collision tumors are relatively rare, and intracranial collision tumors are even more uncommon. Reports of pituitary adenoma combined with craniopharyngioma are exceedingly scarce.

This article presents a case of a 75-year-old male patient diagnosed with a collision tumor consisting of a pituitary adenoma and craniopharyngioma in the sellar region.

After hospital admission, MRI examination revealed a mass in the sellar and suprasellar region, suggestive of a pituitary adenoma combined with a craniopharyngioma. The patient underwent trans-sphenoidal endoscopic tumor resection. Intraoperatively, a mass was observed in the sellar and suprasellar regions. Postoperative pathology confirmed a diagnosis of pituitary adenoma combined with craniopharyngioma.

The patient underwent endoscopic transnasal surgery, successfully resecting the tumor. Postoperatively, the patient received hormone replacement therapy and was regularly monitored.

Postoperative MRI indicated that the majority of the tumor had been resected. The patient developed hormonal imbalances post-surgery, which improved after hormone replacement therapy. The patient's condition stabilized, was cured, and was dismissed from the hospital..

Early detection and timely surgical intervention remain the optimal management strategies. The principle of treatment is to maximize tumor resection while preserving critical anatomic structures, aiming to reduce the risk of recurrence.